NEWS

Ethyl 4-chloroacetoacetate has a very wide range of uses and plays an important role as an intermediate for medicine and pesticides. In terms of appearance, the substance is mainly transparent colorless to pale yellow red liquid. At the same time, it is accompanied by the odor of acetic acid and has a certain water solubility. From the basic characteristics of this product, it belongs to a kind of stable and principle oxide, which plays an important role in the field of medicine and pesticide.

From the point of view of the synthetic method of ethyl 4-chloroacetoacetate, it is generally synthesized in the standard process. In the reaction species equipped with a stirrer, a thermometer and a reflux condenser, ethyl acetoacetate was appropriately added, and after cooling in an ice-salt bath, sulfuryl chloride was added dropwise with stirring to maintain the temperature of the reaction solution at 0 ~ 5 ° C for 3 ~ 4 h Added. After the addition, the temperature was naturally raised, and the reaction was stirred at room temperature for 3 h, and then placed overnight. At 40-50°C, use a water pump to decompress the sulfur dioxide and hydrogen chloride gas, then heat up to 90°C, use an oil pump to decompress and evaporate the unreacted ethyl acetoacetate, and finally cool it to 30°C to synthesize. From these steps, we can see that the corresponding substances must be synthesized strictly according to the relevant steps and environment.

In addition, we also need to pay strict attention to the storage method of ethyl 4-chloroacetoacetate to ensure that the substance will not have various problems. During storage, it is best to keep the chemical in an airtight container in a cool and dry place. At the same time, the storage place must be locked and handed over to professional technicians, such as technical experts or assistants. At the same time, a ventilated and dry place must be selected to ensure that it is far away from oxidants. The safety of people and substances can only be ensured if the procedures are strictly followed.